Louis M. Weiner, MD| Gastrointestinal Medical Oncology, Medical Oncology | MedStar Health
Louis M. Weiner

Louis M. Weiner, MD
Provider is directly employed by MedStar Health

4.8 out of 5 (109 reviews)

Specialties: Gastrointestinal Medical Oncology, Medical Oncology

Languages: English

202-444-1229

About me

Dr. Weiner is an internationally-recognized medical oncologist specializing in gastrointestinal cancers. He is also an accomplished researcher developing novel immunotherapy treatments – essentially triggering the body’s own immune system to identify and destroy cancer. He is recognized for his laboratory and clinical research focusing on these new therapeutic approaches. Dr. Weiner wants to understand why some tumors become resistant to therapy and other forms of cancer immunotherapy, with the goal of developing new treatments to overcome that resistance. He lectures extensively on these forms of targeted therapies, which block the growth and spread of cancer.

He serves as director of the Georgetown Lombardi Comprehensive Cancer Center – Washington, D.C.’s only National Cancer Institute-designated comprehensive cancer center – and the MedStar Georgetown Cancer Institute, which combines medical expertise, the latest therapies, and research across MedStar Health throughout the region. Dr. Weiner is also associate vice president at Georgetown University Medical Center, chair of the oncology department at Georgetown University School of Medicine, and clinical director of cancer services at MedStar Georgetown University Hospital.

In these roles, Dr. Weiner is responsible for operations, development, research, clinical and educational missions. As the Institute’s director, he oversees the clinical operations of the MedStar Health cancer service line, and leads the advancement of clinical care and research programs spanning prevention, treatment, rehabilitation, survivorship and end-of-life care across the region. With Georgetown Lombardi serving as the Institute’s “research engine,” patients throughout the region have access to unmatched expertise and clinical trials closer to where they live and work.

Dr. Weiner previously served as chairman of the Medical Oncology Department and vice president for Translational Research at Fox Chase Cancer Center in Philadelphia, PA. He held an endowed chair in medical science and was the driving force behind developing an immunotherapy laboratory and clinical programs, as well as establishing the Center's medical oncology fellowship program. Dr. Weiner also served as professor in the Department of Medicine at Temple University School of Medicine.

Dr. Weiner's Philosophy of Care
We live in a time of great hope in the area of cancer therapy. Many new, important and life-changing treatments are now being developed. We are privileged to offer patients tomorrow's treatments today. And now, through the MedStar Georgetown Cancer Institute, we can extend that mission across the region. With this progress in mind, I strive to offer all my patients the best possible therapies for their diseases, always mindful that I am neither treating a disease nor a patient, but a person with a life, a family and a combination of hopes and fears.

Working at a great cancer program like this gives me the opportunity to collaborate with leading international experts to assure that my patients can benefit from the best possible care during the course of their journeys.

Clinical areas of focus

  • Colorectal Malignancy
  • Esophageal Cancer
  • Gastrointestinal (GI) Cancer
  • Gastrointestinal (GI) Stromal Tumors
  • Hepatoblastoma
  • Liver Cancer
  • Liver Metastases
  • Pancreas Cancer
  • Rectal Cancer
  • Small Bowel Cancer
Show More

Conditions and procedures

Conditions I treat

  • Abdominal Cancer
  • Anal Cancer
  • Anorectal Cancer
  • Appendiceal Cancer
  • Bile Duct Mass
  • Brca
  • Cancer
  • Cancer During Pregnancy
  • Cancer Pain
  • Cancer Related Fatigue
  • Cancer Survivor
  • Carcinoid Of Stomach
  • Carcinoid Tumor
  • Carcinoid Tumor Of Pancreas
  • Cholangiocarcinoma
  • Colorectal Malignancy
  • Cystadenoma Of Pancreas
  • Endocrine Complications Of Cancer Therapy
  • Esophageal Cancer
  • Gallbladder Cancer
  • Gastrin Secreting Tumor Of Pancreas
  • Gastroesophageal Junction Cancer
  • Gastrointestinal (GI) Cancer
  • Gastrointestinal (GI) Stromal Tumors
  • Head And Neck Tumors
  • Hepatobiliary Malignancies
  • Hepatoblastoma
  • Hereditary Cancer Risk
  • Insulinoma
  • Islet Cell Tumor
  • Kras Mutation
  • Liver Cancer
  • Liver Mass
  • Liver Metastases
  • Lung Mass
  • Lynch Syndrome
  • Malignant Neoplasm Of Pancreatic Duct
  • Malignant Rectal Neoplasm
  • Malignant Tumor Of Extrahepatic Bile Duct
  • Metastatic Colon Cancer
  • Neuroendocrine Tumors
  • Oral Complications Of Cancer
  • Pancreas Cancer
  • Pancreas Head Cancer
  • Pancreas Tail Cancer
  • Pancreatic Mass
  • Pseudomyxoma Peritonei
  • Pulmonary Metastases
  • Rectal Cancer
  • Rectal Carcinoma In Situ
  • Recurrent Colorectal Cancer
  • Side Effects Of Cancer Treatment
  • Small Bowel Cancer
  • Small Intestine Cancer
  • Stomach Cancer
Show All Show Less

Procedures I perform

  • Adjuvant Chemotherapy
  • Biologic Therapy For Gastrointestinal Diseases
  • Biological Targeted Therapy
  • Cancer Chemotherapy
  • Cancer Genomics
  • Chemoradiation
  • Colon Cancer Chemotherapy
  • Early Detection Of Cancer
Show All button Press enter to expand Show Less

Practice locations

Distance from Change LocationEnter your Location

3800 Reservoir Road Northwest
Lombardi Cancer Center
Washington, DC, 20007

202-444-2223

Fax 202-444-1229

Get Directions

miles away

Fax 202-444-1229

Insurance

MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.

  • List of insurance plans we accept
    • Innovation Health: PPO
    • Tricare East Prime
    • Kaiser Permanente Signature-Added Choice
    • CareFirst Group Medicare Advantage prescription drug benefit (PPO)
    • I-SNP
    • CareFirst Blue Card Program (Out-of-area BCBS plans)
    • CareFirst Maryland Indemnity or PPO
    • Aetna Managed Choice (POS)
    • Cigna HMO Open Access
    • Employee Health Plan (EHP)
    • CareFirst MedStar Select PPO
    • Aetna Open HMO/Open HMO Option/Open EPO Plus
    • Kaiser HMO Plus and DHMO Plus Member
    • Innovation Health: Network Only Plus
    • Tricare for Life East
    • CareFirst (NCA) Indemnity
    • CareFirst MedStar PPO
    • Aetna HMO-Open Access/Select OA
    • Medicaid - Virginia
    • United Optimum Choice
    • Aetna Managed Choice Open Access (POS)
    • CareFirst BC/BS Advantage Core/Enhanced
    • HumanaChoice Honor’s plan PPO
    • United Optimum Choice Preferred (POS) & OCI Direct (HMO)
    • Carefirst Blue Preferred PPO
    • CareFirst Group Medicare Advantage
    • Innovation Health: POS Plus
    • Carefirst Healthy Blue (HMO/POS)
    • Aetna HMO
    • Aetna Elect Choice/ Open Access (POS)
    • Medicaid - Maryland
    • Federal Employee Program (Std/Basic PPO/Blue Focus)
    • United MD IPA Preferred (POS)
    • Carefirst BlueChoice Opt Out Open Access
    • HumanaChoice PPO
    • Carefirst EPO
    • Priority Partners - Maryland Health Choice
    • United Student Resources
    • Traditional Medicare Fee for Service
    • Cigna TotalCare (HMO D-SNP)
    • WellPoint Maryland - Maryland Health Choice
    • Veterans Affairs Community Care Network (VA CCN)
    • Innovation Health: HMO & EPO Plus
    • Aetna Quality Point of Service (POS)
    • Kaiser Signature
    • United Nursing Home Plan (C-SNP
    • United Select HMO - EPO/NPP
    • MedStar Family Choice DC Healthy Families
    • Medicaid - District of Columbia
    • United Group Medicare Advantage Plans
    • Aetna HealthFund/Health Network Option OA
    • United Erickson Advantage Plans
    • Kaiser Flexible Choice
    • Coventry Health Care National Network PPO
    • MedStar Family Choice - Maryland Health Choice
    • First Health PPO
    • Coventry of Delaware HMO/PPO
    • Coventry Health Care of Virginia
    • Great-West Healthcare POS/CIGNA
    • Aetna Open Choice (PPO)
    • Kaiser Medicare Plus
    • United Mamsi Life & Health
    • Cigna POS Open Access & Open Access Plus
    • Cigna Achieve Medicare (HMO C-SNP)
    • D-SNP)
    • Beech Street PPO
    • Virginia Premier
    • Police and Fire Clinic
    • Cigna True Choice Plus Medicare (PPO)
    • CareFirst NASCO
    • United AARP Medicare Complete
    • Aetna Signature Administrator PPO/TPA
    • Kaiser Medicare Advantage Signature and Select
    • Veterans Affairs Community Care Network
    • Cigna Choice Fund PPO
    • Innovation Health: Open POS II
    • Innovation Health: Open Network Only Plus
    • Cigna HMO & Network (HMO)
    • United Navigate
    • Kaiser Select
    • Cigna Indemnity
    • United Core Essential (HMO)
    • Innovation Health: Open POS Plus
    • United GEHA (for all other states) Compass Rose
    • Kaiser Select-Added Choice
    • Aetna Select HMO/HealthFund/Health Network
    • Tricare East Select
    • Aetna Medicare Advantage HMO & PPO Plans
    • Aetna Student Health Insurance
    • Health Services for Children with Special Needs (HSCSN)
    • Innovation Health: Indemnity
    • Maryland Point of Service Plan (MPOS)
    • Aetna Elect Choice/ EPO (Aetna Health Fund)
    • WellPoint Maryland
    • Aetna Traditional Choice (PPO)
    • Innovation Health: POS
    • Cigna True Choice Medicare (PPO)
    • United Options (PPO) (includes Empire PPO)
    • MedStar Family Choice DC Healthcare Alliance
    • CareFirst Administrators
    • Carefirst BlueChoice HMO
    • Cigna POS/Network POS
    • Cigna Alliance Medicare (HMO) |
    • Cigna Network Open Access
    • Aetna Choice POS & Choice POS II
    • Cigna Preferred Medicare
    • HealthyBlue PPO
    • United Choice
    • United Community Plan - Maryland Health Choice Program
    • Carefirst BlueChoice Open Access
    • CIGNA EPO
    • United MD IPA (HMO)
    • UnitedHealthcare Individual Exchange Plans
    • Private Health Care Systems (PHCS) (PPO)
    • United Choice Plus
    • United Golden Rule
    • Uniformed Services Family Health Plan (USFHP)
    • United Medicare Advantage DSNP District of Columbia
    • Carefirst BlueChoice Opt Out Plus Open Access (POS)
    • Tricare Reserve Select
    • United Select Plus (POS)
    • Cigna PPO and PPO Plus

Videos

Education

Board Certification: American Board of Internal Medicine, Medical Oncology

Board Certification: American Board of Internal Medicine, Internal Medicine

Fellowship Program: New England Medical Center Hospitals (1982)

Residency Program: Fletcher Allen Health Care (1981)

Internship Program: Fletcher Allen Health Care (1978)

Medical School: Mount Sinai School of Medicine (1977)

Awards

  • Castle Connolly Top Doctors, 2021
  • National Academy of Inventors Fellow, 2017-2018
  • Recognition for Outstanding Contribution to Innovation and Commercialization, Georgetown University, Office of Technology, 2016
  • Fellow, American College of Physicians, 2010
  • America’s Top Oncologists, 2009               
  • America’s Top Doctors for Cancer, 2007 – Present
  • Philadelphia Magazine's Top Docs, 2002; 2004 – 2007
  • Who's Who in Medicine and Healthcare, 2002 - 2005
  • G. Morris Dorrance, Jr. Endowed Chair in Medical Science, 2002
  • American Association for Cancer Research Scientist-Survivor Program Award, 2002
  • American Cancer Society - Southeast Region Scientific Research Award, 2002
  • Janssen Pharmaceutical Research Foundation: Research Award for Outstanding Contributions to the Field of Receptor Targeted Therapy, 2001
  • Best Doctors in America, 2000-2011
  • National Cancer Institute Clinical Investigator Award, 1986
  • American Cancer Society Career Development Award, 1985

News and publications

Dr. Weiner has authored more than 200 publications throughout his career centering on the following core topics:
  • Enhancing Antibody Dependent Cellular Cytotoxicity (ADCC) as an Anti-Tumor Mechanism
  • Manipulating Antibody Structure to Improve Selective Tumor Targeting
  • Identifying Tumor Cell-Based Determinants of Antibody-Mediated Cell Killing
  • Immunoconjugates for Cancer Therapy
  • Antibody-initiated Cancer Immunotherapy
  • Click here for a complete list of his research papers and scientific contributions. 

Ratings and reviews

  • Explanations the care provider gave you about your problem or condition

    4.8
  • Extent to which the care provider listened to you

    4.8
  • Care provider’s discussion of any proposed treatment (options, risks, benefits, etc.)

    4.8
  • Provider included you in decisions

    4.8
  • Concern the care provider showed for your questions or worries

    4.8
  • Likelihood of recommending this care provider to others

    4.8
  • Mar 21, 2024

    The best!

  • Jun 13, 2023

    I have recommend to others.

  • Mar 21, 2023

    *Dr. Weiner has been a source of security for over 10 years now that everything is under control!