Louis Marc Weiner, MD| Gastrointestinal Medical Oncology, Medical Oncology | MedStar Health
Louis Marc Weiner

Louis Marc Weiner, MD
Provider is directly employed by MedStar Health

4.8 out of 5 (113 reviews)

Specialties: Gastrointestinal Medical Oncology, Medical Oncology

Languages: English

202-444-1229

About me

Dr. Weiner is an internationally-recognized medical oncologist specializing in gastrointestinal cancers. He is also an accomplished researcher developing novel immunotherapy treatments – essentially triggering the body’s own immune system to identify and destroy cancer. He is recognized for his laboratory and clinical research focusing on these new therapeutic approaches. Dr. Weiner wants to understand why some tumors become resistant to therapy and other forms of cancer immunotherapy, with the goal of developing new treatments to overcome that resistance. He lectures extensively on these forms of targeted therapies, which block the growth and spread of cancer.

He serves as director of the Georgetown Lombardi Comprehensive Cancer Center – Washington, D.C.’s only National Cancer Institute-designated comprehensive cancer center – and the MedStar Georgetown Cancer Institute, which combines medical expertise, the latest therapies, and research across MedStar Health throughout the region. Dr. Weiner is also associate vice president at Georgetown University Medical Center, chair of the oncology department at Georgetown University School of Medicine, and clinical director of cancer services at MedStar Georgetown University Hospital.

In these roles, Dr. Weiner is responsible for operations, development, research, clinical and educational missions. As the Institute’s director, he oversees the clinical operations of the MedStar Health cancer service line, and leads the advancement of clinical care and research programs spanning prevention, treatment, rehabilitation, survivorship and end-of-life care across the region. With Georgetown Lombardi serving as the Institute’s “research engine,” patients throughout the region have access to unmatched expertise and clinical trials closer to where they live and work.

Dr. Weiner previously served as chairman of the Medical Oncology Department and vice president for Translational Research at Fox Chase Cancer Center in Philadelphia, PA. He held an endowed chair in medical science and was the driving force behind developing an immunotherapy laboratory and clinical programs, as well as establishing the Center's medical oncology fellowship program. Dr. Weiner also served as professor in the Department of Medicine at Temple University School of Medicine.

Dr. Weiner's Philosophy of Care
We live in a time of great hope in the area of cancer therapy. Many new, important and life-changing treatments are now being developed. We are privileged to offer patients tomorrow's treatments today. And now, through the MedStar Georgetown Cancer Institute, we can extend that mission across the region. With this progress in mind, I strive to offer all my patients the best possible therapies for their diseases, always mindful that I am neither treating a disease nor a patient, but a person with a life, a family and a combination of hopes and fears.

Working at a great cancer program like this gives me the opportunity to collaborate with leading international experts to assure that my patients can benefit from the best possible care during the course of their journeys.

Clinical areas of focus

  • Colorectal Malignancy
  • Esophageal Cancer
  • Gastrointestinal (GI) Cancer
  • Gastrointestinal (GI) Stromal Tumors
  • Hepatoblastoma
  • Liver Cancer
  • Liver Metastases
  • Pancreas Cancer
  • Rectal Cancer
  • Small Bowel Cancer

Conditions and procedures

Conditions I treat

  • Abdominal Cancer
  • Anal Cancer
  • Anorectal Cancer
  • Appendiceal Cancer
  • Bile Duct Mass
  • Brca
  • Cancer
  • Cancer During Pregnancy
  • Cancer Pain
  • Cancer Related Fatigue
  • Cancer Survivor
  • Carcinoid Of Stomach
  • Carcinoid Tumor
  • Carcinoid Tumor Of Pancreas
  • Cholangiocarcinoma
  • Colorectal Malignancy
  • Cystadenoma Of Pancreas
  • Endocrine Complications Of Cancer Therapy
  • Esophageal Cancer
  • Gallbladder Cancer
  • Gastrin Secreting Tumor Of Pancreas
  • Gastroesophageal Junction Cancer
  • Gastrointestinal (GI) Cancer
  • Gastrointestinal (GI) Stromal Tumors
  • Head And Neck Tumors
  • Hepatobiliary Malignancies
  • Hepatoblastoma
  • Hereditary Cancer Risk
  • Insulinoma
  • Islet Cell Tumor
  • Kras Mutation
  • Liver Cancer
  • Liver Mass
  • Liver Metastases
  • Lung Mass
  • Lynch Syndrome
  • Malignant Neoplasm Of Pancreatic Duct
  • Malignant Rectal Neoplasm
  • Malignant Tumor Of Extrahepatic Bile Duct
  • Metastatic Colon Cancer
  • Neuroendocrine Tumors
  • Oral Complications Of Cancer
  • Pancreas Cancer
  • Pancreas Head Cancer
  • Pancreas Tail Cancer
  • Pancreatic Mass
  • Pseudomyxoma Peritonei
  • Pulmonary Metastases
  • Rectal Cancer
  • Rectal Carcinoma In Situ
  • Recurrent Colorectal Cancer
  • Side Effects Of Cancer Treatment
  • Small Bowel Cancer
  • Small Intestine Cancer
  • Stomach Cancer
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Procedures I perform

  • Adjuvant Chemotherapy
  • Biologic Therapy For Gastrointestinal Diseases
  • Biological Targeted Therapy
  • Cancer Chemotherapy
  • Cancer Genomics
  • Chemoradiation
  • Colon Cancer Chemotherapy
  • Early Detection Of Cancer
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Practice locations

Distance from Enter your Location

3800 Reservoir Road Northwest
Lombardi Cancer Center
Washington, DC, 20007

202-444-2223

Fax 202-444-1229

Get Directions

miles away

Fax 202-444-1229

Insurance

MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.

    • Innovation Health: PPO

      Aetna Managed Choice (POS)

      Aetna Open HMO/Open HMO Option/Open EPO Plus

      Innovation Health: Network Only Plus

      Aetna HMO-Open Access/Select OA

      Aetna Managed Choice Open Access (POS)

      Innovation Health: POS Plus

      Aetna HMO

      Aetna Elect Choice/ Open Access (POS)

      Innovation Health: HMO & EPO Plus

      Aetna Quality Point of Service (POS)

      Aetna HealthFund/Health Network Option OA

      Aetna Open Choice (PPO)

      Aetna Signature Administrator PPO/TPA

      Innovation Health: Open POS II

      Innovation Health: Open Network Only Plus

      Innovation Health: Open POS Plus

      Aetna Select HMO/HealthFund/Health Network

      Aetna Medicare Advantage HMO & PPO Plans

      Aetna Student Health Insurance

      Innovation Health: Indemnity

      Aetna Elect Choice/ EPO (Aetna Health Fund)

      Aetna Traditional Choice (PPO)

      Innovation Health: POS

      Aetna Choice POS & Choice POS II

    • Tricare East Prime

      Tricare for Life East

      Tricare East Select

      Tricare Reserve Select

    • Kaiser Permanente Signature-Added Choice

      Kaiser HMO Plus and DHMO Plus Member

      Kaiser Signature

      Kaiser Flexible Choice

      Kaiser Medicare Plus

      Virginia Premier

      Kaiser Medicare Advantage Signature and Select

      Kaiser Select

      Kaiser Select-Added Choice

    • CareFirst Group Medicare Advantage prescription drug benefit (PPO)

      CareFirst Blue Card Program (Out-of-area BCBS plans)

      CareFirst Maryland Indemnity or PPO

      CareFirst MedStar Select PPO

      CareFirst (NCA) Indemnity

      CareFirst MedStar PPO

      CareFirst BC/BS Advantage Core/Enhanced

      Carefirst Blue Preferred PPO

      CareFirst Group Medicare Advantage

      Carefirst Healthy Blue (HMO/POS)

      Federal Employee Program (Std/Basic PPO/Blue Focus)

      Carefirst BlueChoice Opt Out Open Access

      Carefirst EPO

      CareFirst NASCO

      Maryland Point of Service Plan (MPOS)

      CareFirst Administrators

      Carefirst BlueChoice HMO

      HealthyBlue PPO

      Carefirst BlueChoice Open Access

      Carefirst BlueChoice Opt Out Plus Open Access (POS)

    • I-SNP

      United Optimum Choice

      United Optimum Choice Preferred (POS) & OCI Direct (HMO)

      United MD IPA Preferred (POS)

      United Student Resources

      United Nursing Home Plan (C-SNP

      United Select HMO - EPO/NPP

      United Group Medicare Advantage Plans

      United Erickson Advantage Plans

      United Mamsi Life & Health

      D-SNP)

      United AARP Medicare Complete

      United Navigate

      United Core Essential (HMO)

      United GEHA (for all other states) Compass Rose

      United Options (PPO) (includes Empire PPO)

      United Choice

      United Community Plan - Maryland Health Choice Program

      United MD IPA (HMO)

      UnitedHealthcare Individual Exchange Plans

      United Choice Plus

      United Golden Rule

      United Medicare Advantage DSNP District of Columbia

      United Select Plus (POS)

    • Cigna HMO Open Access

      Cigna TotalCare (HMO D-SNP)

      Great-West Healthcare POS/CIGNA

      Cigna POS Open Access & Open Access Plus

      Cigna Achieve Medicare (HMO C-SNP)

      Cigna True Choice Plus Medicare (PPO)

      Cigna Choice Fund PPO

      Cigna HMO & Network (HMO)

      Cigna Indemnity

      Cigna True Choice Medicare (PPO)

      Cigna POS/Network POS

      Cigna Alliance Medicare (HMO) |

      Cigna Network Open Access

      Cigna Preferred Medicare

      Cigna EPO

      Cigna PPO and PPO Plus

    • Employee Health Plan (EHP)

      Priority Partners - Maryland Health Choice

      Uniformed Services Family Health Plan (USFHP)

    • Medicaid - Virginia

      Medicaid - Maryland

      Medicaid - District of Columbia

    • HumanaChoice Honor’s plan PPO

      HumanaChoice PPO

    • Traditional Medicare Fee for Service

    • WellPoint Maryland - Maryland Health Choice

    • Veterans Affairs Community Care Network (VA CCN)

    • MedStar Family Choice DC Healthy Families

      MedStar Family Choice - Maryland Health Choice

      MedStar Family Choice DC Healthcare Alliance

    • Coventry Health Care National Network PPO

      First Health PPO

      Coventry of Delaware HMO/PPO

      Coventry Health Care of Virginia

    • Beech Street PPO

    • Police and Fire Clinic

    • Veterans Affairs Community Care Network

    • Health Services for Children with Special Needs (HSCSN)

    • WellPoint Maryland

    • Private Health Care Systems (PHCS) (PPO)

Education

Board Certification: American Board of Internal Medicine, Internal Medicine

Fellowship: Tufts Medical Center (1984)

Fellowship: Tufts Medical Center (1982)

Residency: University of Vermont Medical Center (1981)

Internship: University of Vermont Medical Center (1978)

Medical School: Icahn School of Medicine at Mount Sinai (1977)

Awards

  • Castle Connolly Top Doctors, 2021
  • National Academy of Inventors Fellow, 2017-2018
  • Recognition for Outstanding Contribution to Innovation and Commercialization, Georgetown University, Office of Technology, 2016
  • Fellow, American College of Physicians, 2010
  • America’s Top Oncologists, 2009               
  • America’s Top Doctors for Cancer, 2007 – Present
  • Philadelphia Magazine's Top Docs, 2002; 2004 – 2007
  • Who's Who in Medicine and Healthcare, 2002 - 2005
  • G. Morris Dorrance, Jr. Endowed Chair in Medical Science, 2002
  • American Association for Cancer Research Scientist-Survivor Program Award, 2002
  • American Cancer Society - Southeast Region Scientific Research Award, 2002
  • Janssen Pharmaceutical Research Foundation: Research Award for Outstanding Contributions to the Field of Receptor Targeted Therapy, 2001
  • Best Doctors in America, 2000-2011
  • National Cancer Institute Clinical Investigator Award, 1986
  • American Cancer Society Career Development Award, 1985

News and publications

Dr. Weiner has authored more than 200 publications throughout his career centering on the following core topics:
  • Enhancing Antibody Dependent Cellular Cytotoxicity (ADCC) as an Anti-Tumor Mechanism
  • Manipulating Antibody Structure to Improve Selective Tumor Targeting
  • Identifying Tumor Cell-Based Determinants of Antibody-Mediated Cell Killing
  • Immunoconjugates for Cancer Therapy
  • Antibody-initiated Cancer Immunotherapy
  • Click here for a complete list of his research papers and scientific contributions. 

Ratings and reviews

  • Explanations the care provider gave you about your problem or condition

    4.8
  • Extent to which the care provider listened to you

    4.8
  • Care provider’s discussion of any proposed treatment (options, risks, benefits, etc.)

    4.8
  • Provider included you in decisions

    4.8
  • Concern the care provider showed for your questions or worries

    4.8
  • Likelihood of recommending this care provider to others

    4.8
  • Jan 28, 2025

    Dr. Weiner is amazing. So knowledgeable and great people skills I am very luck to be under his care.

  • Nov 14, 2024

    Great!

  • Mar 21, 2024

    The best!